Exploitation of different image modalities, such as Computed Tomography (CT), anatomical and quantitative Magnetic Resonance Imaging (MRI), for radiotherapy treatment personalization. Among the investigated functional MRI techniques, a speficic focus is given to Diffusion-Weighted MRI (DW-MRI).
Development of a robotic 6 DOF patient positioning system (PPS) based on pantographic architecture featuring high positional open-loop accuracy with varying weight. This is combined with infra-red optical tracking for set-up and immobility verification and double X-ray projection systems for 2D-3D registration. This system is installed at the National Centre of Oncological Hadrontherapy (CNAO, Pavia, Italy).