Use of respiratory-correlated 4D imaging (3D + time) for organ motion quantification during treatment planning, such as 4D Computed Tomography (4DCT) and 4D Magnetic Resonance Imaging (4D MRI)
Implementation of methods for artifacts reduction in 4D imaging, based on external/internal, single/multiple points respiratory signals
Implementation of motion modelling techniques to estimate geometric and dosimetric changes in presence of respiratory motion. These consist in advanced local and global motion models for tumor tracking and treatment verification and adapation.
Exploitation of non-rigid image registration algorithm for motion quantification, with a specific focus on validation strategies

4D imaging and motion modelling

Optimization of respiratory-correlated 4D MRI and time-resolved 2D cine-MRI images for organ motion management
Implementation of strategies for tumor tracking in MRI-linac systems based on landmarks and non-rigid registration, along with development of motion models and methods for 3D anatomo-pathological estimation.
Generation of virtual 4DCT based on radiation-free 4DMRI data for treatment adaptation in photon and particle therapy

MRI Guidance

Organ Motion Management